Oradel™-XR is our extended release technology. Extended release technology allows the active pharmaceutical ingredient (API) to release steadily over an extended period of time. This technology can be used to ensure that the active drug is still being released when reaching the gastrointestinal tract. It can be released for a shorter amount of time such as 4-6 hours, or for a further extended period of time such as 8-10 hours. Coating Place is capable of using various physical and chemical approaches to create the extended release profile that your project requires.
The matrix coating system allows for versatility and the highest quality product in the creation of extended released development. Relying on the porosity, solubility or erosion characteristics of the matrix ensures that the API is released at the proper rates to create the desired release span necessary. This release mechanism can be triggered through a variety of means such as a pH, temperature or solvent change.
Oradel™-XR technology can be paired with any number of other Oradel™ techniques. Using a pH trigger for release would require a pairing with Oradel™-ER for an enteric release in the small intestine or with Oradel™-DR to last further into the gastrointestinal tract. A pairing with our Oradel™-MC could create multiple layers of releasing API, allowing for a longer release period. Oradel™-ION might be used to create a prolonged shelf-life for the product or to create a liquid oral delivery method. It could also be used as a taste-masking technique for an unpalatable API. Our Oradel™-XR technology can be used in many products and in many ways. Contact us to learn more about how Oradel™-XR could be used on your project.