Oradel™-ION is our ion exchange technology. Coating Place has extensive expertise and numerous patents in the area of controlled release using ion exchange technology. Since most active pharmaceutical ingredient (API) molecules include an ionizable functional group, they are able to be ionically bound to a pharmaceutical ion-exchange resin possessing a functional group with an opposing charge. This produces an insoluble drug-resin complex (DRC) that can provide taste masking, improved bioavailability, or controlled release of the API in liquid suspensions, capsules, tablets, or other dosage forms. The ionic bond between the ion-exchange resin and the API imparts stability to the DRC in liquid or solid dosage forms. The release of an API from a DRC can be further customized by applying a film coating to the DRC to achieve a wide range of possible release profiles. This melding of our entire Oradel™ Platform shows the versatility available from Coating Place.
Coating Place combines expertise in formulations and manufacturing of DRCs, coatings, and liquid or solid oral dosage forms to provide complete solutions from concept to commercial manufacturing with our Oradel™-ION technology. To find out more about how Oradel™-ION can be used to enhance your product, please contact us.