Our Oradel™-EC technology allows your active pharmaceutical ingredient to release when it reaches the small intestines and not in the stomach. Enteric coating a core ensures that the release is triggered through a change in pH when the product is digested through the stomach and into the duodenum and continues into the gastrointestinal tract. The change from the acidic location of the stomach and into the basic environment of the small intestine causes the product to begin breaking down. In creating this coating, developers ensure a delayed release is achieved.
Enteric release is often chosen to avoid side effects such as stomach upset when release begins in the acid environment of the stomach. Coating Place is capable of matching your enteric coat desires with other techniques such as Oradel™-XR and Oradel™-MC. A pairing with both Oradel™-MC and Oradel™-XR could create a product where release is triggered by the movement into the small intestines but slowly releases as it moves through the gastrointestinal tract. A product with this release profile would require using our Oradel™-MC to create multiple coating layers. To find out more about how Oradel™-ER can be used with your intestinal delivery product, please contact us.