Time-Release Technology - Coating Place, Inc.

Controlled release of active components from particulate materials can be achieved through the use of core-shell or matrix strategies. These strategies typically rely on porosity, solubility, or erosion characteristics of the formulation shell and/or matrix. Release can be delayed to an appropriate time, sustained for a required time, or sustained for a required time after a delay period. Release can be governed in a variety of ways including the following:

pH changes
temperature changes
solvent changes
enzyme addition
coat or matrix dissolution/erosion rate
coat or matrix porosity

Coating Place can formulate and manufacture core-shell or matrix system controlled release particles ranging from near and below 20µm to 1cm and above. Matrix strategies may be realized through granulation, extrusion and spheronization, roll compaction, blending, or application of a matrix film coating that contains the active. Core-shell strategies involve application of a controlled release coating to a particle containing an active ingredient. Active material can be coated directly, granulated and coated, or applied as a layer on a particle and then coated. Multiple actives and controlled release components can be applied in a suitable layer arrangement on a particle to achieve desired release.

THE WURSTER PROCESS

NEWS AND EVENTS

DID YOU KNOW?

The World Health Organization uses medications manufactured at Coating Place.

Coating Place, Inc. 200 Paoli Street | PO Box 930310 | Verona, WI 53593. Phone: (608) 845-9521 Fax: (608) 845-9526